Request for Applications – Cycle 5A of the NIA IMPACT Collaboratory

National Institute of Aging IMPACT Collaboratory Announces Request for Applications

January 30, 2023 – The National Institute on Aging (NIA) Imbedded Pragmatic Alzheimer’s
Disease (AD) and AD-Related Dementias (AD/ADRD) Clinical Trials (IMPACT) Collaboratory is
happy to announce a Request for Applications for the Pilot Grants Program Cycle 5A.
In this cycle, the IMPACT Collaboratory will fund up to five 1-year awards for pilot pragmatic
clinical trials (ePCTs) that test non-pharmacological interventions embedded in health care
system(s) for people living with Alzheimer’s Disease (AD) and AD-related dementias (ADRD)
and their care partners. Pilot Studies will be funded for up to $175,000 in direct costs for a
maximum of 12-months. For more information, please see our Pilot Grants Program page.

The goal of the pilot projects is to generate the preliminary data necessary to design and
conduct a future full-scale Stage IV effectiveness ePCT (based on the NIH Stage Model) funded
through other grant mechanisms (NIH or other sources).

The IMPACT Collaboratory will consider all applications for pilot ePCTs that evaluate
non-pharmacological interventions to improve the care of people living with AD/ADRD and their
care partners. This grant cycle will prioritize applications for interventions in these populations
that aim to:

• Improve care through behavioral economics “nudge” interventions;
• Reduce inequities in health care;
• Reduce potentially inappropriate medications through de-prescribing; or
•  Improve care in emergency departments.

Informational Webinar

An optional informational webinar will be hosted to provide investigators with an overview of
application details and an opportunity to ask questions. Pre-registration is required using the link
below.
Tuesday, February 14 at 12:00 pm ET: Register here.

Letters of Intent (LOI) Due – Required
Interested applicants are required to submit an LOI. LOIs are accepted on a rolling basis
through Friday, March 3, 2023 @ 5pm ET

Full Applications Due – By invitation only
Applications selected for further consideration will be invited to submit a full proposal due June
16, 2023 @ 5pm ET

Name of contact for follow up: Elaine Bergman, IMPACT Communications Lead
Contact email address: [email protected]